MDMA Neurotoxicity Insights

The discussion highlights the neurotoxic effects of MDMA, particularly when combined with substances like caffeine. Animal studies reveal that even moderate doses can lead to a decrease in serotonin levels, affecting mood and motivation. Importantly, short-term depletion of neuromodulators does not equate to long-term neuronal loss, emphasizing the complexity of MDMA's impact on brain chemistry.