Exercise triggers the release of osteocalcin from bones, which travels to the brain and supports neuron growth in the hippocampus, crucial for memory. This process enhances the effects of brain-derived neurotrophic factor (BDNF) and other growth factors, promoting both short- and long-term memory retention. Regular physical activity can significantly slow the natural decline of hippocampal volume as we age, highlighting the profound impact of exercise on cognitive health.
