Aging and DNA
David likens DNA to music on a CD, where the epigenome acts as the reader that determines which genes are activated in different cells. Over time, "scratches" occur in this system, disrupting the cellular functions and leading to aging and disease. The process involves chemical markings, such as methylation, that dictate gene expression, and as these markings deteriorate, cells lose their identity and purpose, which can even predict mortality.In this clip
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Huberman Lab
Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52
Related Questions
What role does epigenetics play in aging?
How does the epigenome affect aging as discussed in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and the clip Aging and DNA?
How does the epigenome affect aging as discussed in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and the clip Aging and Information?