Dopamine and Pleasure
Engaging in highly pleasurable activities triggers a surge of dopamine, but this is often followed by a downregulation of dopamine receptors, leading to a state of anhedonia, where joy is diminished. Chronic indulgence can reset dopamine thresholds, resulting in anxiety, irritability, and a persistent craving for the initial high. Ultimately, this cycle can create a debilitating dopamine deficit that mirrors clinical depression, making it difficult to find pleasure in everyday life.In this clip
From this podcast
Huberman Lab
Dr. Anna Lembke: Understanding & Treating Addiction | Huberman Lab Podcast #33
Related Questions
Why does Andrew Huberman say that even if you engage in highly enjoyable, high-dopamine work for weeks or days, your dopamine levels will still drop following your dopamine spikes in the episode Dr. Anna Lembke: Understanding & Treating Addiction | Huberman Lab Podcast #33 and the clip Dopamine and Relapse?
What do you mean by "Avoid Constant Pleasure Seeking: Engaging in constant pursuit of high-dopamine activities can lead to a diminished pleasure response and increased craving over time. To maintain balance, it's important to include periods where you are not actively seeking pleasure, allowing your dopamine levels to reset naturally" in the episode How to Control Your Sense of Pain & Pleasure | Huberman Lab Podcast #32 and the clip Intermittent Rewards?
What do you mean by "Avoid Constant Pleasure Seeking: Engaging in constant pursuit of high-dopamine activities can lead to a diminished pleasure response and increased craving over time. To maintain balance, it's important to include periods where you are not actively seeking pleasure, allowing your dopamine levels to reset naturally" in the episode How to Control Your Sense of Pain & Pleasure | Huberman Lab Podcast #32 and the clip Intermittent Rewards?