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Clearing Adenosine

Caffeine and sleep are well-known for their ability to clear adenosine, but physical activity and exposure to daylight can also enhance alertness without directly altering adenosine levels. While sleep, particularly non-REM sleep, plays a crucial role in the natural clearance of adenosine, states of reduced metabolic activity, like anesthesia or deep rest, may offer similar benefits. Understanding these mechanisms opens up intriguing possibilities for managing alertness and sleep pressure.