Published Oct 7, 2024

Dr. Craig Koniver: Peptide & Hormone Therapies for Health, Performance & Longevity

Andrew Huberman hosts Dr. Craig Koniver to delve into the transformative potential of peptide and hormone therapies in enhancing health, performance, and longevity, discussing treatments like GLP-1 agonists and BPC-157, along with the pivotal role of mindset. The episode also tackles the challenges of sourcing safe peptide therapies through regulated compounding pharmacies.
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Episode Highlights

  • GLP-1 Agonists

    Dr. Craig Koniver discusses the use of GLP-1 agonists, like Semaglutide, for weight loss and their broader health impacts. He highlights how these medications, initially approved for type 2 diabetes, have become popular for weight management due to their effectiveness in reducing body fat. Craig emphasizes the importance of safe and controlled use, noting that microdosing can prevent muscle loss while enhancing cognitive benefits and reducing inflammation 1 2.

    Losing weight is a struggle. The way I look at it, if I can help people lose weight first, literally, by using something like teresepatide, semaglutide. And I've seen this, they're now excited.

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    He also shares success stories where patients have experienced significant improvements in their quality of life and motivation after weight loss 3.

       

    BPC-157

    BPC-157 is explored for its role in healing and inflammation reduction, particularly in ligaments and tendons. Craig explains that BPC-157 can be injected directly into tendons, promoting rapid healing without the risks associated with steroids 4. He warns about the dangers of sourcing BPC-157 from unreliable markets, emphasizing the need for physician oversight to ensure safety and efficacy 5.

    BPC is definitely shorthand for BPC 157. That is, is certainly in widespread use. I have been concerned just personally about gray market sources that contain contaminants.

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    The FDA's recent restrictions on compounding pharmacies have complicated access, making it crucial to distinguish between legitimate and unsafe sources 6.

       

    NAD Infusions

    NAD infusions are highlighted for their transformative effects on inflammation and recovery. Craig shares his extensive experience with NAD, noting its ability to rapidly improve health from a compromised state to a super well state 7. He describes the infusion process, emphasizing a 750 mg dose as optimal for balancing effectiveness and patient comfort 8.

    I have been more impressed with the work of NAd than probably any other agent we've ever used.

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    Andrew Huberman recounts his personal experience with NAD infusions, observing significant recovery from COVID symptoms, though he acknowledges the need for more research to understand its full potential 9.

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