Prolactin and MDMA

MDMA significantly elevates prolactin levels, which may contribute to the post-use crash characterized by lethargy and diminished mood. While some are exploring the potential of P5P, a vitamin B6 derivative, to mitigate this effect, there is currently a lack of clinical data on its efficacy. Understanding the role of prolactin could be crucial for enhancing recovery strategies after MDMA use, especially in therapeutic contexts like PTSD treatment.