Ketamine and Dissociation

Ketamine induces a profound dissociative state, allowing individuals to observe themselves from a third-person perspective, which can be both foreign and enlightening. This state is linked to neuroplastic changes in the brain, particularly involving the uncoupling of neocortical and subcortical circuits. As alpha brainwaves diminish, a theta pattern emerges, creating a dreamlike experience that may offer relief from depression and trauma.