Progesterone Options

Estrogen can be safely used alone for those without a uterus, but incorporating progesterone may enhance mood and sleep for some. Micronized progesterone is a favored choice due to its low risk of adverse effects, while IUDs can minimize systemic side effects. Alternative options like basadoxifen and conjugated estrogen provide benefits without the need for progesterone, although they lack the bioidentical status.