Ketamine vs. Lithium
Ketamine enhances neural excitability and shows promise as a treatment for major depression, but its effects are temporary, requiring repeated administration. In contrast, lithium works by reducing overactivity in neural circuits, preventing neurotoxicity, and stabilizing mood in bipolar disorder. Both treatments address different aspects of bipolar disorder, highlighting the importance of tailored psychiatric care.In this clip
From this podcast

Huberman Lab
The Science & Treatment of Bipolar Disorder | Huberman Lab Podcast #82
Related Questions
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode "Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast" and the clip "Neural Circuits of Depression"?
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast and the clip Neural Circuits of Depression?
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast and the clip Neural Circuits of Depression?