Cellular Growth vs Repair
Andrew explains how being in a fed or fasted state can either promote cellular growth or repair and clearance. This is due to the two different pathways of cell growth and cell breakdown and repair associated with AMPK and MTOR/PSX.In this clip
From this podcast
Huberman Lab
Effects of Fasting & Time Restricted Eating on Fat Loss & Health | Huberman Lab Podcast #41
Related Questions
Can we achieve a balance between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and the clip Leucine and Longevity. Can we achieve a balance between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author, and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?