Ketamine and Depression
Ketamine and similar dissociative anesthetics are showing promise in treating depression by inducing a separateness from grief and emotions. This intriguing effect may stem from their ability to block the NMDA receptor, which is traditionally associated with neural activation and plasticity. Despite the experimental nature of these treatments, many individuals report significant relief from depressive symptoms with fewer sessions than expected.In this clip
From this podcast

Huberman Lab
Understanding & Conquering Depression | Huberman Lab Podcast #34
Related Questions
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode "Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast" and the clip "Neural Circuits of Depression"?
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast and the clip Neural Circuits of Depression?
How does the NMDA receptor work in the context of ketamine's effects on depression, PTSD, and neuroplasticity as discussed in the episode Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity | Huberman Lab Podcast and the clip Neural Circuits of Depression?