mTOR and Depression
A groundbreaking study reveals that combining Rapamycin, an mTOR blocker, with ketamine significantly alters treatment outcomes for those with treatment-resistant depression. While traditional ketamine treatment shows a mere 13% response rate, the addition of Rapamycin increases nonresponse rates to over 40%. This research hints at a deeper connection between microglial activity and stress-related disorders, paving the way for future studies to explore the longevity of antidepressant effects.In this clip
From this podcast

Tim Ferriss Show
All Things Ketamine, The Most Comprehensive Podcast Episode Ever — Dr. John Krystal
Related Questions
Are there any studies on Rapamycin in relation to the episode All Things Ketamine, The Most Comprehensive Podcast Episode Ever — Dr. John Krystal and the clip mTOR and Depression?
I have a question about the episode All Things Ketamine, The Most Comprehensive Podcast Episode Ever — Dr. John Krystal and the clip mTOR and Depression Research studies on Rapamycin.
I have a question about the episode All Things Ketamine, The Most Comprehensive Podcast Episode Ever — Dr. John Krystal and the clip mTOR and Depression. Can you provide insights on the research studies regarding Rapamycin discussed in these?