Opioids and Hormones
Opioids significantly disrupt sex steroid hormones, primarily affecting testosterone in men and estrogen in women. This disruption occurs through interference with the hypothalamus and the production of GnRH, leading to various endocrine issues such as gynecomastia in males and ovarian disruptions in females. The implications of opioid use on hormonal health are profound and warrant serious consideration.In this clip
From this podcast

Huberman Lab
The Science of How to Optimize Testosterone & Estrogen | Huberman Lab Podcast #15
Related Questions