Isolation and Aggression
Social isolation leads to increased aggression, fear, and anxiety in mice due to elevated levels of Tachykinins. Remarkably, a drug called Osanatante can reverse these effects, allowing isolated mice to reintegrate peacefully with their peers. Despite its promising safety profile, pharmaceutical companies are hesitant to explore this drug further due to past failures in unrelated clinical trials, raising questions about the disconnect between animal studies and human applications.In this clip
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Huberman Lab
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal | Huberman Lab Podcast #89
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