what about NAD plus
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NAD+, or nicotinamide adenine dinucleotide, has been discussed on the , particularly in the context of aging and vitality. Dr. David Sinclair, a biologist specializing in the study of aging, shared on the podcast that he takes a gram of NMN (Nicotinamide Mononucleotide), a precursor to NAD+, every day, explaining the reasoning behind dosing in the morning to align with the body's natural circadian rhythm of NAD+ levels. Dr. Sinclair emphasized that the specific effects and benefits might not necessarily be generalizable, as individual responses can vary based on factors like age, sex, and personal health 1.
Additionally, shared his personal experience with NAD infusions, stating that while he found them beneficial for his vigor and sleep after feeling rundown, the process was uncomfortable. He clarified that there were no clinical trials supporting NAD infusions for increased vigor, so he considered it safe for himself, but stressed the importance of consulting with a physician 2.
On the topic of NMN supplements, Huberman mentioned that as of 2023, NMN was no longer available as a supplement due to FDA regulations related to its status as an experimental drug in clinical trials. Despite this, he explained that he personally takes NR (Nicotinamide Riboside) and NMN for increased energy levels throughout the day, but without expectations of lifespan extension due to insufficient data 3.
If you are considering using supplements for NAD+ support or thinking about NAD infusions, these insights serve as a starting point. However, it's crucial to consult with healthcare professionals for personalized advice and stay updated on the latest research and regulations.
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