Performance enhancing substances

Here are some insights on performance-enhancing substances discussed in the Huberman Lab:

1. Citrulline and Beetroot:

   • Non-stimulant supplements like citrulline and beetroot juice can enhance endurance performance without affecting sleep negatively. They work through the arginine pathway, promoting vasodilation and nutrient transport to cells. Care is advised for individuals prone to cold sores, as these substances can exacerbate such conditions 1.

2. Nootropic Supplements:

   • Alpha GPC is mentioned as a focus-enhancing supplement. While not a traditional stimulant, it helps improve alertness and can be beneficial for mental tasks or physical training (used sparingly) 1.

3. Caffeine and Other Enhancers:

   • Combining caffeine with supplements like Alpha GPC and L-Tyrosine can significantly enhance both workout and cognitive performance. However, prolonged use may lead to energy troughs and burnout feelings thereafter, rather than true adrenal fatigue 2.

4. Creatine and Beta-Alanine:

   • Creatine is noted for its ability to increase strength and may contribute to hair loss in some users, although it appears to have no significant effects on women in this regard. Beta-Alanine supports endurance in workouts lasting 60 to 240 seconds, improving muscular endurance and reducing fatigue. A common dosage is between 2 to 5 grams 3.
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       1

       Non-Stimulant Performance Boosts

       01:31:20
       
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       2

       Enhancing Performance

       01:30:36
       
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       3

       Performance Enhancers

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These clips highlight the potential of various substances in enhancing physical performance, alongside necessary precautions. For anyone considering these substances, it’s important to consult with healthcare professionals to ensure safety and efficacy.