Reason for not having melatonin supplements

Melatonin supplements raise concerns because doses can be unusually high and inconsistent, the hormone can affect other hormonal systems, and the sleep benefit for most healthy adults appears small. 1 2

• Dose and labeling: Some products provide doses many times higher than the body’s normal levels, and tested supplements have contained substantially less or more than their labels indicate. 3
• Hormonal effects: Melatonin may interact with reproductive hormones; Huberman also noted its role in suppressing puberty onset in children. 4
• Limited sleep effects: It may help with falling asleep, but not necessarily staying asleep; a meta-analysis cited an average increase of just 3.9 minutes of total sleep. 5 1
• Occasional use: It was described as potentially useful for jet lag or occasional use, rather than chronic supplementation. 6