I have a question about this episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and this Methylene Blue Insights What do other experts say about ingesting methylene blue for health purposes as discussed in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52?

In the episode with Dr. David Sinclair, he discusses the controversial practice of ingesting methylene blue, initially used as a cleaning agent for fish tanks, and its rumored health benefits. Dr. Sinclair expresses concerns about the safety of this practice, comparing it to colloidal silver, which can lead to skin staining and other issues. He notes that while some studies suggest methylene blue may extend lifespan in lower organisms, its safety and efficacy in humans are not well established 1.

Another expert, Dr. Craig Koniver, provides insights on methylene blue during a different episode. He highlights its potential cognitive-enhancing properties and its ability to improve mitochondrial function by binding to cytochrome c oxidase. Dr. Koniver mentions that methylene blue can be absorbed well orally, and users have reported significant improvements in brain function. He recommends a dosage of about 10 milligrams, taken in the morning, and points out that methylene blue may cause urine to turn blue or green, indicating its activity in the body 2.

Both experts caution about the need for critical thinking regarding the ingestion of methylene blue, signaling both potential advantages and notable risks.