What is creatine, what does it do physiologicaly in our body

Creatine is a compound that plays a critical role in energy production, particularly in muscle and brain tissue. It serves as a rapid energy reserve in cells, primarily aiding in the regeneration of adenosine triphosphate (ATP), the energy currency of the cell.

Physiological Roles of Creatine:

1. Energy Supply: Creatine is stored in the muscles as phosphocreatine, which can donate a phosphate group to ADP to rapidly regenerate ATP during high-intensity, short-duration activities. This is crucial for activities requiring bursts of power and speed, enhancing athletic performance 1.

2. Brain Function: Beyond muscles, creatine also accumulates in the brain, particularly in regions like the forebrain responsible for cognitive functions such as planning and action. This storage in the brain indicates its role in supporting brain energy metabolism and cognitive functions 2.

3. Calcium Regulation: Creatine influences calcium regulation in neurons, vital for synaptic activity and overall brain function. After traumatic brain injuries, calcium homeostasis can be disrupted, and creatine helps stabilize these processes 2.

4. Mitochondrial Support: It acts as a backup fuel source for mitochondria, aiding in oxidative energy production and minimizing oxidative stress, which is essential for both muscular and brain health 3.

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     1

     Creatine Uncovered

     01:45:03
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     2

     Creatine and Brain Health

     01:04:17
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     3

     Creatine and Hormones

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     4

     Creatine and Cognition

     01:06:44

Overall, creatine's physiological impact extends from enhancing muscle power to supporting brain function, making it a versatile supplement for various health benefits 1 4.