Lp(a)
Sources:
There is limited direct discussion on Lp(a), which stands for Lipoprotein(a), in the Huberman Lab podcast. However, , in a conversation with , briefly touches on particles closely related to Lp(a). Dr. Attia explains that Apolipoprotein B (ApoB) is the causative agent in atherosclerosis and how it's important to keep levels of ApoB low to prevent heart disease. He mentions that LDL includes the LP Little A, although he notes that the concentration of LP Little A is relatively small and does not generally show up as much in the ApoB measurement 1. Moreover, Dr. Attia describes LP Little A as a special type of LDL, which in about 10-20% of the population can be particularly harmful 2.
ApoB is a protein found in lipoproteins that are responsible for transporting cholesterol and triglycerides through the bloodstream. Lp(a) is a type of LDL cholesterol that is bound to a specific type of ApoB that includes an additional protein called apolipoprotein(a). Elevated levels of Lp(a) are considered a risk factor for cardiovascular disease. While Dr. Attia does not provide in-depth knowledge specifically about Lp(a), his discussion underlines its relation to ApoB and its role in cardiovascular risk 1 2.
RELATED QUESTIONS
