Is it beneficial to supplement with methylene blue?

Methylene blue is discussed as a supplement with several potential benefits:

1. Cognitive Enhancement: It is noted to act as a nootropic, improving brain function and providing cognitive stimulation. Dr. Craig Koniver MD mentions that many people report enhanced brain function when using methylene blue, often combining it with caffeine and B vitamins for optimal effects. The recommended dosage is around 10 milligrams, which can be taken in the morning, and it is well-absorbed orally 1.

2. Mitochondrial Function: Methylene blue aids in the efficiency of mitochondria, the energy-producing structures of cells. It enhances oxygen uptake by red blood cells, which can lead to improved cellular energy levels. This action is akin to providing more oxygen onto the blood cells, which further supports cognitive enhancement 2.

3. Antiviral Properties and Mood Enhancement: There are claims of methylene blue having antiviral properties, potentially enhancing resilience against some viruses. It also acts as a mild monoamine oxidase inhibitor (MAOI), which could prolong the activity of neurotransmitters like serotonin, thereby potentially enhancing mood and mental clarity 2.

Historically, methylene blue was used to treat carbon monoxide poisoning by helping red blood cells displace carbon monoxide with oxygen, indicating its role as an oxygenator in the body 3. However, while it's available as a prescription, there are also nutraceutical forms available over-the-counter 2.

As always, consulting a healthcare provider before starting any new supplement regimen is advised, especially for understanding potential interactions and side effects] 2.