How to choose the right retinoid?

When choosing the right retinoid, consider opting for a prescription-strength retinoid over an over-the-counter retinol for more significant benefits. Prescription retinoids, such as tretinoin, adapalene, or tazarotene, enhance skin turnover from the usual 28 days to around 7 to 9 days, which helps prevent skin cancer and fosters the growth of new collagen and elastin. These benefits have been histologically verified through studies involving skin biopsies.

Over-the-counter options tend to be less effective due to their instability or being inactive prodrugs. Prescription retinoids are versatile, often initially developed for acne due to their ability to shrink oil glands, but they also support skin repair and rejuvenation. For individuals with significant sun damage or susceptibility to skin cancer, oral forms like isotretinoin might be recommended. It's critical to note that the awareness around these differences is low, and prescription retinoids are more potent and effective for long-term skin health improvement 1.