How long do reconstituted peptides last?

Andrew Huberman emphasizes that when using therapeutic peptides, it is crucial to ensure they are obtained through a prescription from a board-certified physician. This ensures the peptides have been properly purified, particularly from lipopolysaccharides (LPs), which can trigger immune responses if not removed. Gray or black market sources often lack this purification, posing significant health risks. Always prioritize reputable sources, like pharmaceutical companies or compounding pharmacies, for safe peptide therapies 1.

The shelf life of peptides can be influenced by the conditions in which they are stored and how they are prepared. Andrew Huberman emphasizes the importance of obtaining peptides from reputable sources, such as pharmaceutical companies or compounding pharmacies, where they undergo necessary purification processes like the removal of lipopolysaccharides (LPs). These processes help prevent immune responses that could degrade the peptide quality over time. Storage conditions, such as temperature and exposure to light, along with the presence of impurities, can significantly affect the stability and shelf life of peptides 1.

It appears there isn't specific information available on the indicators of peptide degradation from the material currently accessible from the Huberman Lab. Generally, peptide degradation might be suspected if there are visible changes in color, consistency, or the formation of precipitates, along with diminished biological activity. However, for precise information and testing, specific analytical techniques like High-Performance Liquid Chromatography (HPLC) or Mass Spectrometry may be used to verify peptide stability. Always consult with a professional for accurate testing and advice.

It appears there is no specific information on the signs of peptide degradation available from the Huberman Lab. Generally, signs might include physical changes such as discoloration, changes in consistency, or the presence of precipitates, as well as a reduction in expected biological activity. For precise analysis, laboratory techniques such as High-Performance Liquid Chromatography (HPLC) or Mass Spectrometry are typically used to assess peptide integrity accurately. Consulting with a specialist is advisable for detailed evaluation.

I couldn't find specific information from the Huberman Lab on storing peptides properly. Generally, peptides should be stored in a cool, dry environment away from light. For long-term storage, keeping them in a freezer at -20°C or colder is recommended. For short-term use, storing them at 4°C in a refrigerator is typically suitable. It's essential to prevent frequent freeze-thaw cycles by aliquoting the peptides into smaller portions. Consulting product-specific guidelines and a specialist can provide further detailed advice.