• What is the protocol to lower LDL cholesterol?

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    To lower LDL cholesterol, several strategies can be considered, both through diet and medication.

    Dietary Changes

    1. Reduce Saturated Fats: Replacing saturated fats with polyunsaturated fats can reduce LDL cholesterol and improve heart health. For instance, using olive oil instead of butter is beneficial 1.
    2. Carbohydrate Restriction: Lowering carbohydrate intake can decrease triglyceride levels, which are related to LDL particles. Insulin resistance, often linked with high triglycerides, can also contribute to elevated LDL levels 2 3.

    Pharmacotherapy

    1. Statins: These drugs inhibit cholesterol synthesis in the liver, which increases the number of LDL receptors on liver cells, thereby reducing circulating LDL levels. Statins are known for their effectiveness and generally have a benign side effect profile, with muscle soreness being the most common side effect 2 3.
    2. Ezetimibe: This medication works by blocking the absorption of cholesterol in the intestine, further helping in reducing LDL levels with minimal side effects 2.

    These approaches highlight a combination of dietary adjustments and medications, aiming for a comprehensive strategy to manage cholesterol and reduce the risk of heart disease. It's advisable to consult with a healthcare provider before making significant changes to your diet or starting new medications.

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