What is DHEA?

DHEA (dehydroepiandrosterone) is a hormone primarily produced by the adrenal glands. It's often referred to as a precursor to both testosterone and estrogen, which means it can convert into these sex hormones. DHEA has been promoted as a way to increase levels of testosterone and estrogen in both males and females, impacting various body functions including mental vigor, physical strength, and libido 1. However, the effects of DHEA supplementation can vary depending on individual factors, such as one's starting hormone levels and the presence of aromatase, an enzyme that converts hormones. It's described as a global promoter of sex steroid hormones, and its specific effects can be influenced by whether an individual has more estrogen or testosterone to begin with, as well as whether they have ovaries or testes 1.

In the context of hair loss, DHEA has also been mentioned when discussing the conversion of testosterone to its derivative dihydrotestosterone (DHT). Androgens like testosterone and its derivative, DHT, can play a role in inhibiting hair growth by reducing factors such as IGF-1 (Insulin Growth Factor 1) and cyclic AMP 2.