Why would glutamine be better combined with glycine?

Combining glutamine with glycine may offer benefits in reducing sugar cravings. Glutamine, in particular, has been highlighted for its potential to impact sugar cravings positively. This is because certain neurons in the gut, which respond to amino acids, might trigger dopamine pathways that are usually stimulated by sugar when glutamine is present. This can potentially make glutamine an appealing option for managing cravings without adding significant calories 1.

While glycine is not specifically mentioned in combination with glutamine, it is also an amino acid that may influence similar pathways or contribute synergistically to overall gut health and neurotransmitter function, enhancing the effects seen with glutamine. However, more definitive studies are needed to confirm these effects and define the benefits of such combinations. It's important to note that increasing glutamine should be done cautiously, especially in individuals with preexisting conditions like cancer 1.

Glycine, an amino acid, offers various benefits, including:

1. Sleep Improvement: Glycine helps lower core body temperature, signaling the body that it's time to sleep. This makes it especially useful for improving sleep quality.

2. Cognitive Support: Glycine functions as a neurotransmitter in the brain, where it has inhibitory effects. This can help decrease neuronal excitability, aiding in mental calmness and focus.

3. Skin Health: Glycine is a component of collagen, making it vital for skin health and wound healing by promoting the formation of collagen.

4. Protection Against Muscle Loss: It supports the prevention of muscle breakdown by helping to increase creatine levels, which can aid muscle growth and energy during workouts.

5. Metabolic Health: Glycine contributes to the production of several significant substances, such as glutathione, a major antioxidant which plays a crucial role in cellular and liver health.

These benefits suggest that glycine can be a valuable supplement for improving overall health and bodily functions 1.