Testosterone therapy for menopausal women

Testosterone therapy for menopausal women is approached with caution due to the lack of extensive data supporting its use. When testosterone is prescribed, it is typically for women who exhibit significantly low levels, leading to issues such as difficulty in muscle mass development or reduced libido. In such cases, topical testosterone may be used to bring testosterone levels to a physiologically normal range without crossing into the superphysiological, which could induce negative effects like clitoral enlargement and other symptoms. However, the overall intervention remains conservative due to the limited supporting data for its efficacy and safety in women 1.