What’s the difference between Magnesium Threonate and Magnesium L-Threonate

Magnesium Threonate and Magnesium L-Threonate refer to the same compound, commonly used to enhance sleep and cognitive functions. The primary advantage of Magnesium Threonate is its ability to cross the blood-brain barrier, increasing the levels of magnesium in the brain. This bioavailability is crucial for its effectiveness in promoting relaxation and improving sleep by engaging the GABA pathway, which helps in deactivating certain brain activities for sleep (1).

Magnesium Threonate is valued for its potential neuroprotective benefits and its impact on cognitive function, although most data supporting these claims come from animal studies (2 3).

Both Magnesium Threonate and Magnesium Bisglycinate support sleep, but with slight differences in their biological impacts. Magnesium Threonate is often favored for its brain-related benefits, whereas Bisglycinate might be more aligned with general sleep improvements (4 5).

Overall, individuals respond differently, and it is recommended to try these forms to see which works best for you while considering individual health conditions and consulting healthcare providers before starting supplementation.