How to lower cholesterol

Lower cholesterol by addressing diet and insulin resistance, and use medication when lifestyle changes are not enough.

• 1. Reduce carbohydrates when triglycerides are elevated: Carbohydrate restriction can lower triglycerides, particularly when insulin resistance or high carbohydrate intake is contributing. 1
• 2. Reduce saturated fat if ApoB is high: Lowering saturated fat may help reduce ApoB, a measure of atherogenic particle concentration; the response to diet can vary between people. 2 3
• 3. Consider medication with a clinician: Statins inhibit cholesterol synthesis; the liver responds by increasing LDL receptors and removing more LDL from circulation. 4 PCSK9 inhibitors can be very effective by preserving LDL receptors, including in familial hypercholesterolemia, where cholesterol can be extremely high. 5