What dose of NMN should I take daily?

A starting point mentioned is 1 gram (1,000 mg) of NMN daily, but that is what David Sinclair and his father take—not a dose established as right for everyone. Sinclair notes that responses may differ with microbiome, age, and sex. 1

• Sinclair’s dose: He says he and his father take 1 gram daily. 2
• Huberman’s reported dose: Huberman describes taking 1.5 grams (1,500 mg) sublingually in the morning, and reports increased energy and faster hair and nail growth as personal observations. 3
• Individual differences and product quality: Sinclair cautions that results may vary with microbiome, age, and sex, and advises choosing a well-established source with quality controls, including Good Manufacturing Practices (GMP). 4