Realistically how harmful is drinking one can of diet coke a day?

Drinking one can of Diet Coke a day can have nuanced effects on the body, even though it is often perceived as a healthier alternative to regular soda due to its lack of calories. Here are some key points discussed by experts on the Huberman Lab that illuminate potential impacts:

1. Hunger and Appetite: The sweet taste of Diet Coke can stimulate appetite and increase cravings. Andrew Huberman mentioned that non-nutritive sweeteners like those in Diet Coke might increase hunger for some individuals, potentially leading to higher food intake over time. The perception of sweetness can also drive a conditioned response, where the body expects calories and food, thus stimulating hunger 1.

2. Insulin Response: Although Diet Coke does not contain calories, the sweeteners can trigger an insulin response as the body prepares for an anticipated glucose intake. This conditioned response could potentially impact metabolic health, especially in susceptible individuals or children, as noted by studies mentioned in conversations with Andrew Huberman 1.

3. Metabolic Effects: There is some evidence suggesting that non-nutritive sweeteners in diet sodas can alter the gut biome, which in turn could affect metabolism. This view was shared by Dr. Peter Attia in a discussion with Andrew Huberman, indicating that for certain individuals, these sweeteners might negatively affect metabolic health 1.

In summary, while a single can of Diet Coke per day might not have severe immediate effects for most people, it can potentially stimulate appetite and cravings, and impact insulin responses and metabolic health over time. Andrew Huberman suggests that water is generally a better alternative. Therefore, moderation and awareness of individual responses are key 1.