How often can I drink caffeine without getting a tolerance

To prevent developing a tolerance to caffeine, Andrew Huberman recommends using caffeine every other day instead of daily. Tolerance refers to needing more of a substance to achieve the same effect, or seeing decreased effectiveness over time. He also discusses "caffeine adaptation," where people who regularly consume caffeine might feel alert and relaxed, whereas non-adapted individuals might feel jittery and anxious.

He suggests starting with a dosage of 1 to 3 milligrams of caffeine per kilogram of body weight for a single sitting, such as a morning coffee. Importantly, avoiding multiple high doses throughout the day is crucial to maintaining sensitivity to caffeine's effects 1 2. This strategy helps in preventing tolerance and maintaining effective performance benefits.

He also highlights individual variability, meaning some people may naturally tolerate higher levels of caffeine better than others due to genetic and lifestyle factors 1.