Pinealon

Pinealon is a small peptide discussed for possible effects on sleep and circadian rhythms, though its effects and sourcing warrant caution.

• Melatonin and sleep: Pinealon was described as potentially supporting melatonin production and circadian rhythms. Andrew Huberman reported increased REM sleep with his own use, but that is a personal observation, not established clinical evidence. 1 2
• Epitalin combination: Pinealon was formerly combined with Epitalin, which was discussed in connection with circadian rhythms and melatonin. Potential DNA-repair and vision-related effects were raised, with vision findings described in animal studies. 3 4
• Forms: Injectable Pinealon was commonly used by the speakers. They also discussed the possibility that oral Pinealon can survive stomach acid and be absorbed, while noting a preference for injections for bioavailability. 5
• Authenticity and sourcing: Huberman cautioned that products sold as Pinealon could be mislabeled or counterfeit, and both speakers stressed verifying legitimacy and using a reputable compounding pharmacy with physician guidance. 6