What are the best pain suppliments

For managing pain with supplements, several options have been discussed on the Huberman Lab. Here are some of the notable suggestions:

1. Acetyl L-Carnitine: This supplement has been studied for its neuroprotective properties. It may improve nerve health, as shown in trials where it enhanced nerve conduction velocity in diabetic neuropathy patients. It's available over the counter and is thought to work by improving mitochondrial metabolism 1.

2. Alpha Lipoic Acid: Known for its antioxidant properties, alpha lipoic acid acts as a free radical scavenger and calcium channel modulator. It may provide benefits for neuropathic pain, although some users report it can slightly reduce heart rate during intense exercise 1.

3. Vitamin C: Prophylactic use of vitamin C before surgery, particularly nerve-related surgery, may reduce postoperative nerve pain 1.

4. Omega-3 Fatty Acids (Fish Oil): These have been found to be beneficial for chronic pain, with studies indicating their potential to reduce inflammation and pain perception 2.

5. Creatine: Emerging research suggests that creatine may benefit conditions like fibromyalgia, showing promise in pilot studies 2.

While these supplements can be helpful, Sean Mackey emphasizes the importance of understanding their potential side effects and interactions with other medications, especially when considering surgery 2.