Ashwagandha, discussed by on the , has several notable benefits and effects:

  1. Reduction in Cortisol Levels: Ashwagandha is effective in reducing chronic stress and cortisol levels. Studies indicate a reduction of 14.5% to 27.9% in cortisol levels in stressed but otherwise healthy individuals 1 2.

  2. Anti-Anxiety Effects: It has a powerful anxiolytic (anti-anxiety) effect, demonstrated in multiple peer-reviewed studies 2.

  3. Impact on Hormones: Ashwagandha can increase testosterone, likely indirectly, due to its cortisol-lowering effects, as cortisol and testosterone have an inverse relationship 1 3.

    Hormone Supplements

    Andrew discusses different types of supplements that can augment multiple hormones and support multiple hormone systems, generally in the direction of pro-fertility, pro-libido, and increasing estrogen and testosterone. He also talks about the indirect effects of supplements like Ashwagandha and Maca on testosterone and estrogen pathways.

    Huberman Lab

    Developing a Rational Approach to Supplementation for Health & Performance | Huberman Lab Podcast
  4. Other Health Benefits: Reducing cortisol levels with ashwagandha can lead to decreased heart palpitations, improved cardiovascular health, lessened OCD symptoms, reduced heart rate, better sleep quality, and slight improvements in memory 2 4.

  5. Usage Guidance: It’s advisable not to take ashwagandha for more than two weeks at a time at high dosages. It can be taken in the evening or later in the day to avoid interfering with the natural cortisol peak needed for morning energy 1 5.

suggests consulting detailed resources like for specific dosage information and further details on how long to take it, how to cycle it, and possible effects on different population groups 1 2.