Provide research about apigenin and sleep.
Sources:
has discussed apigenin in respect to its sleep-promoting qualities in various episodes of the . Apigenin, a compound derived from chamomile, can help with sleep by promoting relaxation and reducing anxiety. Here's what has been shared:
- Effectiveness: Apigenin acts as a mild hypnotic by activating chloride channels and hyperpolarizing neurons, which helps increase GABA in the brain. This process contributes to a feeling of drowsiness and relaxation, which is helpful for falling asleep 1.
- Dosage and Use: The typical dosage for sleep purposes is around 50 mg of apigenin taken about 30 minutes before bedtime. It’s often used in combination with other supplements like magnesium threonate and theanine to enhance sleep quality by reducing anxiety and rumination 2 3.
- Estrogen Inhibition: A notable point about apigenin is its potential to inhibit estrogen. This is important to consider for both men and women who might be concerned about their estrogen levels, as manipulating these levels can affect libido and cognitive function 4.
- Research Context: Apigenin itself is supported by some research, although not extensively in top-tier journals. It's mentioned that while the studies might not be found in the most prestigious publications, they do have control groups, suggesting a methodical approach to understanding its effects 5.
Apigenin’s benefits for sleep largely revolve around its ability to decrease mental activity and promote relaxation, potentially making it a useful supplement for those struggling with sleep onset due to racing thoughts or mild anxiety.
RELATED QUESTIONS
