please do a talk with ADHD expert Russell Barkley, he recently retired and spent his career in this field

Currently, the does not have an episode featuring Russell Barkley. Since Dr. Barkley has recently retired and has a significant background in ADHD, a conversation with him could provide valuable insights into ADHD research and management strategies. If you're interested, I can recommend other episodes that deal with related topics such as neuroscience and cognitive enhancement.


Tell me more about Russell Barkley's work.


discusses the mechanism behind ADHD medications in the context of dopamine and norepinephrine in the brain. He describes how these medications increase dopamine to enhance focus and reduce impulsivity, but emphasizes that this must be carefully balanced, as excessive dopamine can lead to side effects like euphoria, mania, or psychosis. A similar balance needs to be maintained with norepinephrine because too much can cause anxiety and other serious symptoms like increased heart rate. He highlights the importance of dosage and individual sensitivity, especially as these factors vary across different age groups and stages of development. This is particularly relevant in improving symptoms like impulsivity, hyperactivity, and focus in individuals with ADHD, although he notes that not all persons with ADHD present all these symptoms; some may only have issues with focus 1.

ADHD Medication Risks

Andrew explains the risks associated with ADHD medication and how it affects dopamine and norepinephrine in the brain. He also discusses the importance of appropriate dosage and the potential for serious side effects if the drugs are not taken as prescribed.

Huberman Lab

Adderall, Stimulants & Modafinil for ADHD: Short- & Long-Term Effects | Huberman Lab Podcast