Apigenin side effects
Sources:
Apigenin is described as a sleep aid, but its anti-estrogenic effects may lower estrogen levels—so it may not suit people who want to maintain higher estrogen.
- Sleep and anxiety: Found in chamomile, apigenin may support sleepiness by calming the nervous system and reducing anxiety; it acts on GABA-related pathways and chloride channels, which can quiet neural activity and shut off thinking.
- Hormonal effects: Apigenin can inhibit estrogen activity and may reduce the conversion of certain androgens to estrogens. This could matter for people seeking to maintain particular estrogen levels.
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