What supplements can you take or food can one eat to increase the intake of NAD’s

To increase NAD+ levels through diet and supplementation, several strategies can be employed. Here are some key points based on insights from the podcast:

Supplements

1. Nicotinamide Riboside (NR):

   • NR is considered a potent precursor to NAD+.
   • Typically taken in capsule form, daily dosages commonly range from 250 mg to 500 mg.
   • Both Andrew Huberman and guest Peter Attia have discussed their experiences with NR supplementation.

2. Nicotinamide Mononucleotide (NMN):

   • Another precursor to NAD+, NMN can also be taken as a sublingual powder or capsule.
   • Common dosages are between 1 g to 2 g, often absorbed more effectively when dissolved under the tongue.
   • The efficacy of NMN regarding its absorption and conversion to NAD+ is still debated.

3. Intravenous NAD+:

   • Some individuals opt for intravenous administration of NAD+, which may provide a direct increase in NAD levels, though this method is less common for the average user.
   • It is important to note that intravenous NAD+ is not as widely accessible.

Food Sources

While specific foods that directly increase NAD+ levels were not discussed in detail, certain dietary patterns can support NAD+ production:

• Foods rich in tryptophan (an amino acid) like turkey and chicken may indirectly promote NAD+ synthesis.
• Foods containing other B vitamins (like B3, B6, B12) contribute to overall metabolic pathways involving NAD+.

Lifestyle Factors

In addition to dietary sources and supplements:

• Caloric Restriction and Intermittent Fasting: These practices have been associated with increased NAD+ levels.

Caution

• There’s recognition from experts that boosting NAD+ levels doesn't necessarily guarantee positive health outcomes, as the relationship between NAD+ levels and overall health is complex. It involves a leap of faith until more definitive evidence is available regarding its benefits and effectiveness in humans 1 2.

Overall, supplementation with NR and NMN appears to be the most directly discussed approach in improving NAD+ levels, with the importance of monitoring effects and potential side effects as well.