what has huberman said about N-Acetyl-Cysteine?
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has discussed various benefits and uses of N-Acetylcysteine (NAC) on the podcast. He highlights its efficacy in reducing the risk of influenza, where studies indicated a significant reduction in contracting the virus by using NAC as compared to placebo groups. NAC is often taken as a preventive measure with dosages around 1200 milligrams per day, divided into two doses of 600 milligrams each 1.
NAC is also a potent mucolytic, which helps alleviate sinus congestion without the drawbacks of traditional decongestants, such as rebound congestion. It's commonly used at doses of 600 to 900 milligrams three times a day to relieve cold symptoms 2.
Furthermore, Dr. Huberman points out that NAC can also support the body's antioxidant defense as a precursor to glutathione, the master antioxidant. It reduces oxidative stress during infections by combating reactive oxygen and nitrogen species. NAC is even used medically to treat conditions like cystic fibrosis due to its mucolytic properties 3.
Despite its over-the-counter availability, the FDA has scrutinized NAC's status as a supplement. This regulatory challenge happened due to previous claims from some companies about its efficacy for conditions like hangovers, which lacked solid data. However, NAC remains accessible in the U.S. for purchase 4.
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