N-Acetylcysteine NAC

N-Acetylcysteine (NAC) has notable applications for immune support and overall health, as discussed by Andrew Huberman in the Huberman Lab.

Key Insights on NAC:

• Influenza Risk Reduction: NAC significantly reduces the risk of contracting influenza. In a study, only 25% of those taking NAC contracted the virus, compared to 79% in the placebo group. This indicates its potential as a preventative supplement 1.

• Glutathione Precursor: NAC is primarily recognized as a precursor to glutathione, often referred to as the body's "master antioxidant." This role is crucial during illnesses as glutathione helps combat reactive oxygen and nitrogen species that increase during infections 2.

• Dosage Recommendations: For preventative measures, a dosage of approximately 1200 mg per day, divided into two doses of 600 mg each, is suggested. NAC can also be taken therapeutically at higher doses, like 900 mg three times daily when symptomatic, though it's advisable to avoid taking it close to bedtime due to its mucus-thinning effects 1.

• Availability: NAC is available over-the-counter in the U.S., despite past efforts by the FDA to restrict its sale due to misleading claims by some supplement companies. Advocacy has kept it accessible 1.

Summary:

NAC is a valuable supplement for enhancing immune function and potentially shortening the duration of colds and flu. It's beneficial in supporting glutathione levels, which play a critical role in the body's antioxidant defense systems. Always consider consulting healthcare professionals before starting any new supplement regimen.