Hello Dr. Huberman, I am writing to you as a recently diagnosed 39 year old single father of 4, with a neuro disease called ALS/ PLS. It is an overwhelming diagnosis, after being a person that excercised 4-5 times a week, ran 1-2 miles a week, practiced 30 minutes of sauna 4-5 times a week, and ate rather healthy, practiced fasting ( usually 16-8)no sugar, no pop. I am curious if you have any insights into this disease. What can a person do, what protocols can someone take, is there any promising clinical trials are out there(stem cells)?I am at a loss of what to do, when I feel I was doing everything to stay healthy. My own experience (short version)started with a left shoulder pain ( several doctors and physical therapist) almost 2 years ago, was told I had calcific tendonitis, impingement, frozen shoulder, a surgery, painful therapy. Right shoulder followed. MRI’s of (shoulders, cervical, thoracic, brain). I have tried cold showers, red light therapy, contemplating a carnivore diet,( I ate steak only for 3 days) and wandered if I was lacking nutrients. My arms shake, muscle spasms,hyper reflexes, wake up stiff( takes a good 20-30 minutes) to move my legs and arms to swing myself out of bed. Is there anything one can do other than, sit back it’s going to be rough ride??

I'm sorry to hear about your diagnosis and the challenges you are facing. While Andrew Huberman and his guests have discussed neurodegenerative diseases, including some aspects of ALS (Amyotrophic Lateral Sclerosis) and related conditions, they haven't focused extensively on specific treatments or clinical trials for these diseases. However, here are some insights that may help:

1. Stem Cell Research: Dr. Gary Steinberg, featured on the Huberman Lab, is actively involved in stem cell research and other cutting-edge therapies. Although the exact application to ALS was not detailed, such advancements in neurosurgery and neuroprotection could hold promise for future treatments 1.

2. Understanding Neurodegeneration: Neurodegenerative diseases like ALS are complex, and while specific treatment strategies are not always detailed in Huberman's discussions, there's an ongoing effort in the scientific community to understand their mechanisms better. Discussions have noted that controlling cognitive decline through lifestyle and understanding of neuroplasticity may offer indirect benefits 2.

3. Managing Symptoms: On a broader level, discussions have emphasized lifestyle factors like sleep and stress management as foundational to brain health. Again, while not ALS-specific, maintaining optimal health could support better overall well-being 3.

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     Brain Health Insights

     01:51:38
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     Neurodegenerative Disease Insights

     01:58:47
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     Sleep and Health Insights

     00:05:25

4. Community and Support: It's crucial to connect with healthcare professionals specializing in ALS, support groups, and organizations that might have more tailored advice and current information on clinical trials.

For the latest clinical trials and treatments, it might be helpful to consult resources like clinicaltrials.gov or specialized ALS organizations. They could provide more specific directions and options relevant to your situation.