I have a question about this episode Developing a Rational Approach to Supplementation for Health & Performance | Huberman Lab Podcast and this Hormonal Supplements Explained How do ashwagandha and other supplements affect hormones?
Sources:
In the episode of the discussing supplementation, explains that certain supplements, like ashwagandha and shilajit, can affect hormones in different ways.
Ashwagandha
- Cortisol Reduction: Ashwagandha is notable for its ability to significantly reduce cortisol levels, which is often beneficial as cortisol and testosterone levels interact such that lowering cortisol can indirectly increase testosterone 1. This adaptogenic herb can lower cortisol by 14.5 to 27.9% in individuals experiencing stress 2.
- Testosterone: It has been shown to modestly increase testosterone levels, mainly through its indirect effects on hormone pathways by reducing cortisol 1.
Shilajit
- Hormonal Support: Shilajit is highlighted for its ability to enhance multiple hormones such as follicle-stimulating hormone (FSH), which, in turn, can boost testosterone, enhance libido, and improve fertility in both males and females 1.
General Considerations
- Broadly, these supplements are considered adaptogens, which help the body manage stress and may also affect other hormone pathways such as estrogen and thyroid hormones. It's also important to cycle these supplements, especially ashwagandha, to avoid potential issues with liver and thyroid when taken in high doses for extended periods 3 4.
Overall, while these supplements can offer significant benefits in hormonal balance and stress reduction, timing, dosage, and cycling are crucial to minimize potential side effects while maximizing benefits.
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