Hyperestrogenemia

The topic of hyperestrogenemia has been discussed in relation to various conditions and contexts within the Huberman Lab. Here are some insights:

• In one discussion, Kyle Gillett mentions that hyperestrogenism can coincide with endometriosis, characterized by the overgrowth of the lining of the uterus. He suggests that individuals suffering from this may benefit from supplements like Tongkat Ali, which can decrease aromatase, an enzyme that converts androgens to estrogens, thereby potentially balancing estrogen levels 1.
• In another segment, Kyle Gillett also discusses how alcohol and high-fat meals can increase aromatase, which could lead to hyperestrogenism. This is particularly relevant for individuals following a high-fat diet, such as a ketogenic diet, who might already be experiencing elevated estrogen levels 2.
• Elsewhere, Andrew Huberman explains how various supplements, including Fadogia Agrestis, can affect levels of luteinizing hormone and consequently alter levels of testosterone and estrogen. He underscores the importance of blood work and monitoring hormonal levels when considering supplementation, as it's crucial for safety and understanding the impact on one's biological systems 3.
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    1

    Tongkat Ali Insights

    01:49:34
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    2

    Estrogen and Fats

    01:41:57
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    3

    Hormonal Balance Insights

    01:54:10

Understanding and managing estrogen levels are critical for health, and it's recommended that individuals consult healthcare professionals for personalized advice and monitoring, especially when considering taking supplements or altering hormone levels.