Melatonin and affects on dopamine

Melatonin may reduce baseline dopamine: one study found a statistically significant drop in dopamine 60 minutes after melatonin administration. 1

• Bright light exposure: Bright light between 10:00 p.m. and 4:00 a.m.—or during circadian phase three, about 17–24 hours after waking—can reduce dopamine that night and the following day. Keep lights dim during that period. 2
• Melatonin use: Where possible, avoid supplemental melatonin and favor adjustable behavioral approaches instead. The discussion also emphasizes getting sufficient B vitamins, while cautioning against excessive B6 supplementation. 3 4