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Has muscle mass been shown as a predictor of long life expectancy

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Yes. Greater muscle mass—and particularly greater muscle strength—has been associated with lower all-cause mortality, though the association is stronger for strength than for muscle mass.

  • People with low muscle mass or strength face higher mortality risk: In the comparison described, low muscle mass was associated with about three times the all-cause mortality risk of high muscle mass; low strength was associated with an even larger difference.
  • Strength shows the stronger association: The discussion notes that the muscle-mass finding may reflect its close association with strength, and estimates a roughly 3.5-fold hazard ratio for low versus high strength.
  • Strength training supports function with age: It was described as a way to combat neuromuscular aging and preserve strength and power needed for movement and catching oneself from a fall.
  • Other longevity-linked measures: Handgrip strength and lean mass were described as inversely associated with mortality, with the association becoming stronger at older ages.

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