I have a question about this episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and this Methylene Blue Insights What do other experts say about ingesting methylene blue for health purposes as discussed in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52?
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In this episode of the , there is a discussion between and about methylene blue, originally a cleaning agent, which some people are now ingesting to potentially benefit health and longevity. Methylene blue has been noted to extend lifespan in some lower organisms, but concerns about its safety and side effects, such as staining the body, raise questions about the practice's validity [1].
Another expert, Dr. Craig Koniver, discusses methylene blue's benefits for cognitive enhancement and mitochondrial function. He mentions it acts as a mild monoamine oxidase inhibitor (MAOI), which can enhance neurotransmitter activity. Methylene blue has been utilized in treating conditions like carbon monoxide poisoning and is reported to show antiviral properties. Despite its prescription status, over-the-counter versions are available [2].
Dr. Koniver also mentions that methylene blue has been gaining popularity, particularly for its rapid effects in treating symptoms like those of COVID-19. It enhances mitochondrial function by working on cytochrome c oxidase, facilitating better oxygen uptake in cells [3].
For cognitive benefits, a typical dose is around 10 milligrams, taken in the morning. It's known to turn bodily excretions blue or green, which is harmless but should be considered [4].
In summary, while methylene blue may offer intriguing health benefits, such as cognitive and mitochondrial enhancements, its ingestion should be approached cautiously, considering potential safety concerns.