Is a loading phase necessary for creatine?

Andrew Huberman has explained that a loading phase for creatine is not necessary. Previously, it was common to load creatine by taking a high dose for several days before switching to a maintenance dose, but this has been found unnecessary. Now, it is clear that simply taking a daily dose of creatine suffices, and you can start seeing benefits without a loading phase. This method is effective and can achieve full saturation within three to four weeks using regular daily doses of 3 to 7 grams 1 2.

Moreover, the timing of when you take creatine doesn't significantly impact its effectiveness. Whether you take it post-workout, pre-workout, or at any other time doesn't seem to matter much 1.