What does Andrew say about PCOS?
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has discussed Polycystic Ovary Syndrome (PCOS) in several episodes of the . Here are some key insights:
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Incidence and Diagnosis: PCOS is often underdiagnosed, with prevalence estimates ranging from 10% to 20% of women. Symptoms such as androgen excess, insulin resistance, and oligomenorrhea are common indicators, and many women discover their condition in their 30s due to fertility issues 1.
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Causes and Risk Factors: Insulin resistance is a significant factor. Elevated insulin levels can stimulate the ovaries to overproduce testosterone, leading to PCOS symptoms. This condition is also linked with obesity and metabolic issues 2.
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Symptoms and Criteria: Symptoms include androgenic acne, hair growth in unusual places (hirsutism), male-pattern baldness, and oligo-ovulation (irregular menstrual cycles). Though often associated with cystic ovaries, a diagnosis doesn't require the presence of ovarian cysts 3.
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Impact on Health: Beyond reproductive issues, PCOS is a risk factor for cardiometabolic diseases as women age. Elevated androgens and insulin resistance contribute significantly to long-term health risks 4 2.
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Treatments: Common treatments include birth control to regulate ovulation and manage androgen levels. For obese patients, weight loss can restore ovulation. New treatments like GLP-1 receptor agonists show promise in reducing PCOS symptoms and improving fertility 5.
Understanding PCOS's full spectrum and considering it a lifelong condition rather than just a reproductive issue can help tailor more effective treatments and support 4.
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